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Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury.

Identifieur interne : 000E89 ( Main/Exploration ); précédent : 000E88; suivant : 000E90

Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury.

Auteurs : Sean M. Bagshaw [Canada] ; Michael Darmon [France] ; Marlies Ostermann [Royaume-Uni] ; Fredric O. Finkelstein [États-Unis] ; Ron Wald [Canada] ; Ashita J. Tolwani [États-Unis] ; Stuart L. Goldstein [États-Unis] ; David J. Gattas [Australie] ; Shigehiko Uchino [Japon] ; Eric A. Hoste [Belgique] ; Stephane Gaudry [France]

Source :

RBID : pubmed:28289816

Abstract

Acute kidney injury (AKI) is associated with incremental risk for death and chronic kidney disease and represents a mounting clinical challenge for healthcare professionals. Renal replacement therapy (RRT) use in ICU settings is rising, likely in response to similar trends in AKI, taken together with an ageing population burdened by high prevalence of multi-morbidity and high illness acuity. Numerous features of RRT prescription and delivery are not standardized, nor are they supported from high-quality evidence derived from randomized trials. Despite the publication of rigorous clinical practice guidelines focused on RRT for AKI that are intended to optimize the quality and reliability of RRT in ICU settings, practice patterns and outcomes continue to show significant variability. In this concise review, we aim to summarize new knowledge and recent advances for the provision of RRT for critically ill patients with AKI.

DOI: 10.1007/s00134-017-4762-8
PubMed: 28289816


Affiliations:


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<div type="abstract" xml:lang="en">Acute kidney injury (AKI) is associated with incremental risk for death and chronic kidney disease and represents a mounting clinical challenge for healthcare professionals. Renal replacement therapy (RRT) use in ICU settings is rising, likely in response to similar trends in AKI, taken together with an ageing population burdened by high prevalence of multi-morbidity and high illness acuity. Numerous features of RRT prescription and delivery are not standardized, nor are they supported from high-quality evidence derived from randomized trials. Despite the publication of rigorous clinical practice guidelines focused on RRT for AKI that are intended to optimize the quality and reliability of RRT in ICU settings, practice patterns and outcomes continue to show significant variability. In this concise review, we aim to summarize new knowledge and recent advances for the provision of RRT for critically ill patients with AKI.</div>
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